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The drama stars Alex O'Loughlin, Scott Caan, Ian Anthony Dale, Meaghan Rath, Beulah Koale, Katrina Law, Taylor Wily, Dennis Chun, Kimee Balmilero and Chi McBride.
Peter M. Lenkov, Alex Kurtzman and Roberto Orci developed the series, with Lenkov serving as its showrunner. They executive produce with David Wolkove and Matt Wheeler. CBS Television Studios produces.
At the end of its run, Hawaii Five-0 will have produced 240 episodes.
"It's never easy to say goodbye to a hit franchise that carried on the legacy of the original with such distinction while establishing its own signature style," said Kelly Kahl, President, CBS Entertainment. "From episode one, Hawaii Five-0 has been a huge success for us. Thanks to the amazing talents of the producers, writers, cast and crew, it has played a key role for a decade on our schedule and helped establish our powerhouse Friday night. We cannot be prouder of its quality, longevity and are thankful for the passionate fan-devotion it inspired."
"Hawaii Five-0 has been such a blessing to me and all of the people who have worked on this incredible show," added Lenkov. "I truly learned the meaning of 'ohana' as the viewers embraced us and the people of Hawaii welcomed us with the privilege to film on their shores. I am forever indebted to the creative genius that was Leonard Freeman who gave us such a beautiful story to begin with. And my eternal gratitude to our cast, led by our hero Alex O'Loughlin, the writers, the production team, our CBS ohana, and most importantly - YOU, the fans, who allowed us to come to work with pride and made our series such a success. Mahalo."